SAS Rapid testing for the real world
DRW makes widely available diagnostic tests based on two chemical assay platforms developed in the Diagnostic Development Unit at the University of Cambridge :
SAS (Signal Amplification System) for protein targets
SAMBA (Simple Amplification Based Assay) for nucleic acids.
SAS is based on multiplying a visual signal via an increase in the valency and size of the coloured immune complex in the assay, by chemically coupling multiple copies of a hapten to the primary detection antibodies. The resulting lattice formed between the analyte, multiple hapten-labelled antibody and the anti-hapten colour conjugate yields a strong visual signal.
The first test made available via the SAS platform is a Chlamydia Rapid Test. Diagnostics for the Real World is distributing this test in developed and developing settings.
Another product currently in development and based on the same SAS technology includes a dual test for simultaneous detection of Influenza A and B viruses.
In order to improve the ease of urine sample collection in men and to increase the sensitivity of the Chlamydia test and other urogenital infections, DRW has developed the FirstBurst Urine collection device.